Rabbit Biotechnology: Rabbit genomics, transgenesis, cloning - download pdf or read online

By Louis-Marie Houdebine,Jianglin Fan

ISBN-10: 9048122260

ISBN-13: 9789048122264

ISBN-10: 9048184762

ISBN-13: 9789048184767

Louis-Marie Houdebine and Jianglin Fan The research of organic features of proteins and their attainable roles within the pathogenesis of human ailments calls for an increasing number of correct animal m- els. even though mice together with genetically transformed mice provide many probabilities, different non-murine species are completely required in a few conditions. Rabbit is this type of species, which has been primary in biomedical stories. This animal is genetically and physiologically towards people together with cardiov- cular process and metabolism features. Rabbit is therefore extra applicable than mice to check a few illnesses akin to atherosclerosis and lipid metabolism. due to its higher measurement, surgical procedure manipulation, bleeding, and turn-over stories are a lot more straightforward played in rabbits than in mice. additionally, transgenic rabbits could be produced utilizing microinjection and different tools comparable to lentiviral v- tors. Cloning in rabbits has been proved attainable, even if nonetheless onerous and time-consuming. optimistically, practical rabbit ES telephone traces can be to be had within the coming years. Gene deletion or knock-out in rabbits will then turn into possible.

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Rabbit Biotechnology: Rabbit genomics, transgenesis, cloning and models by Louis-Marie Houdebine,Jianglin Fan


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