Bruno Sarmento,Jose das Neves's Chitosan-Based Systems for Biopharmaceuticals: Delivery, PDF

By Bruno Sarmento,Jose das Neves

ISBN-10: 0470978325

ISBN-13: 9780470978320

Chitosan is a linear polysaccharide commercially produced by means of the deacetylation of chitin. it really is non-toxic, biodegradable, biocompatible, and acts as a bioadhesive with another way volatile biomolecules - making it a important part within the formula of biopharmaceutical medications.

Chitosan-Based platforms for Biopharmaceuticals presents an in depth assessment of the applying of chitosan and its derivatives within the improvement and optimisation of biopharmaceuticals. The ebook is split in 4 diverse elements. half I discusses normal elements of chitosan and its derivatives, with specific emphasis on matters concerning the advance of biopharmaceutical chitosan-based structures. half II offers with using chitosan and derivatives within the formula and supply of biopharmaceuticals, and makes a speciality of the synergistic results among chitosan and this actual subset of prescribed drugs. half III discusses particular purposes of chitosan and its derivatives for biopharmaceutical use. eventually, half IV offers varied viewpoints on varied matters resembling regulatory, production and toxicological necessities of chitosan and its derivatives concerning the advance of biopharmaceutical items, in addition to their patent prestige, and medical software and potential.

Topics coated include:

  • chemical and technological advances in chitins and chitosans precious for the formula of biopharmaceuticals
  • physical homes of chitosan and derivatives in sol and gel states
  • absorption advertising homes of chitosan and derivatives
  • biocompatibility and biodegradation of chitosan and derivatives
  • biological and pharmacological job of chitosan and derivatives
  • biological, chemical and actual compatibility of chitosan and biopharmaceuticals
  • approaches for useful amendment or crosslinking of chitosan
  • use of chitosan and derivatives in traditional biopharmaceutical dosage forms
  • manufacture suggestions of chitosan-based microparticles and nanoparticles for biopharmaceuticals
  • chitosan and derivatives for biopharmaceutical use: mucoadhesive properties
  • chitosan-based structures for mucosal supply of biopharmaceuticals
  • chitosan-based supply structures for mucosal vaccination
  • chitosan-based nanoparticulates for oral supply of biopharmaceuticals
  • chitosan-based structures for ocular supply of biopharmaceuticals
  • chemical amendment of chitosan for supply of DNA and siRNA
  • target-specific chitosan-based nanoparticle platforms for nucleic acid delivery
  • functional PEGylated chitosan structures for biopharmaceuticals
  • stimuli-sensitive chitosan-based platforms for biopharmaceuticals
  • chitosan copolymers for biopharmaceuticals
  • application of chitosan for anti-cancer biopharmaceutical delivery
  • chitosan-based biopharmaceuticals scaffolds in tissue engineering and regenerative medicine
  • wound therapeutic houses of chitosan and its use in wound dressing biopharmaceuticals
  • toxicological homes of chitosan and derivatives for biopharmaceutical applications
  • regulatory prestige of chitosan and derivatives
  • patentability and highbrow estate issues
  • quality regulate and stable production practice
  • preclinical and scientific use of chitosan and derivatives for biopharmaceuticals

Chitosan-Based platforms for Biopharmaceuticals is a vital compendium of basic thoughts, useful instruments and functions of chitosan-based biopharmaceuticals for researchers in academia and operating in drug formula and supply, biopharmaceuticals, medicinal chemistry, pharmacy, bioengineering and new fabrics development.

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Bruno Sarmento,Jose das Neves's Chitosan-Based Systems for Biopharmaceuticals: Delivery, PDF

Chitosan is a linear polysaccharide commercially produced by means of the deacetylation of chitin. it truly is non-toxic, biodegradable, biocompatible, and acts as a bioadhesive with another way risky biomolecules - making it a useful part within the formula of biopharmaceutical medicines. Chitosan-Based platforms for Biopharmaceuticals offers an in depth evaluation of the applying of chitosan and its derivatives within the improvement and optimisation of biopharmaceuticals.

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Chitosan-Based Systems for Biopharmaceuticals: Delivery, Targeting and Polymer Therapeutics by Bruno Sarmento,Jose das Neves


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