Download e-book for iPad: Transcriptional and Translational Regulation of Stem Cells: by Gary Hime,Helen Abud

By Gary Hime,Helen Abud

ISBN-10: 9400766203

ISBN-13: 9789400766204

ISBN-10: 9402401822

ISBN-13: 9789402401820

This quantity describes the most recent findings on transcriptional and translational rules of stem cells. either transcriptional activators and repressors were proven to be the most important for the upkeep of the stem mobile kingdom. A key portion of stem phone upkeep is repression of differentiation components or developmental genes – accomplished transcriptionally, epigenetically by way of the Polycomb complicated, and post-transcriptionally via RNA-binding proteins and microRNAs. This quantity takes ways to this subject – (1) illustrating the final rules defined above via a sequence of alternative stem cellphone examples – embryonic, iPS and grownup stem cells, and (2) describing a number of molecular households which have been proven to have roles in rules of a number of stem telephone populations.

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Transcriptional and Translational Regulation of Stem Cells: 786 (Advances in Experimental Medicine and Biology) by Gary Hime,Helen Abud


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